Bolton Wanderers can congratulate themselves on holding their Premier League opponents to a 0-0 draw at Anfield in the first match, however they will be looking to find the back of the net at home on Wednesday.
That's not to say that we're expecting a home win in this clash, however the Trotters will be hoping to end Liverpool's solidity in defence in this competition.
Indeed, with Championship goals in their last two outings against Rotherham and Wolverhampton Wanderers, the hosts on this occasion will be in high spirits coming into this match.
Nevertheless, Bolton possess frailties in their own rearguard and this will likely prove to be their undoing at the Macron Stadium. The Reds will be eager to exploit those frailties to the full and will perhaps be calling on Daniel Sturridge to continue scoring in his second successive game since his return from his lengthy injury spell.
The winner of this clash will face up to Crystal Palace in the next round of the competition, however the Reds' defence has only conceded two goals in their last ten hours of play.
This is the FA Cup however and this competition can often spring surprises. With Bolton appearing to be in the ascendancy in the Championship, this could easily prove to be one of those upsets.
We're cautious to back such an outcome however. Bolton look set to score against Liverpool, however their defence has displayed frailties this season and this will be their undoing on Wednesday.
Live coverage on BBC1 at 7:45pm, Wednesday 4th February
Our betting tips
Liverpool win, both teams scoring -Boylesports 9/4
Over 3.5 Goals - BetVictor 21/10