To be fair, a top four finish this season is realistically beyond Pochettino's side, however Spurs are confident of clinching a European place at the end of the season and they can move a step closer to this goal when they make the short journey to Loftus Road in what is this weekend's only Premier League clash.
Spurs have been involved in no less than five London derbies in all competitions since the turn of the year including the Capital One Cup final last weekend, suffering a 2-0 defeat to rivals Chelsea, a contrast to the New Year's Day result in which the White Hart Lane crowd saw a thrilling performance from the hosts which saw them beat Mourinho's men to the tune of 5-3.
A 2-1 win over arch-rivals Arsenal early last month saw Spurs continue to slowly climb up the league table and despite a disappointing 3-2 defeat to Liverpool and a salvaged point at West Ham in February, Pochettino's side look set to make a concerted effort to take the top six by storm.
QPR were involved in their own city derby match with Arsenal on Wednesday evening, losing 2-1 with Gunners goals from Giroud and Sanchez. Late hope was provided by Charlie Austin who scored with eight minutes left, however this defeat leaves QPR third from bottom and in desperate need of three points. These won't be forthcoming on Saturday.
This in reality should be relatively clear cut. Despite some slip-ups of late, Spurs appear to have found their feet again and should have little problem in disposing with a QPR side which has managed just one win in all competitions since Christmas.
Harry Kane was in action against Swansea in their midweek clash and despite not managing to get his name onto the scoresheet on that occasion, he remains by some distance Spurs' top scorer for the season and will be eager to add to his season tally of 22 on Saturday. We believe that he will have little difficulty in penetrating a Rangers defence which along with Burnley is the weakest in the Premier League.
One thing which QPR have been managing is goals however and despite this result looking relatively clear cut, we expect the hosts to score against the leakiest rearguard in the top half of the table.
Our betting tips
Spurs win, both teams scoring - 888sport 3/1
Anytime Goalscorer, Harry Kane - Winner 6/5